An EAV-HP insertion in the promoter region of SLCO1B3 has pleiotropic effects on chicken liver metabolism based on the transcriptome and proteome analysis

An EAV-HP insertion in the promoter region of SLCO1B3 has pleiotropic effects on chicken liver metabolism based on the transcriptome and proteome analysis

Abstract Solute carrier organic anion transporter 1B3 (SLCO1B3) is an important liver primarily highly expressed gene, its encoded protein (OATP1B3) involved in the transport of multi-specific endogenous and exogenous substances. We previously reported that an EAV-HP inserted mutation (IM+) in the 5...

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Main Authors: Jianfei Chen, Guoying Hua, Deping Han, Xiaotong Zheng, Xianggui Dong, Shuxiang Wang, Junjiang Long, Zhonghua Zheng, Ailing Wang, Jiankui Wang, Xiaotong Wang, Xuemei Deng
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-87054-9

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https://doi.org/10.1038/s41598-021-87054-9

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