A fast numerical method for oxygen supply in tissue with complex blood vessel network.

Angiogenesis plays an essential role in many pathological processes such as tumor growth, wound healing, and keloid development. Low oxygen level is the main driving stimulus for angiogenesis. In an animal tissue, the oxygen level is mainly determined by three effects-the oxygen delivery through blo...

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Bibliographic Details
Main Authors: Yuankai Lu, Dan Hu, Wenjun Ying
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0247641