BKCa participates in E2 inducing endometrial adenocarcinoma by activating MEK/ERK pathway

BKCa participates in E2 inducing endometrial adenocarcinoma by activating MEK/ERK pathway

Abstract Background The large-conductance, voltage-gated, calcium (Ca (2+))-activated potassium channel (BKCa) plays an important role in regulating Ca (2+) signaling and cell physiological function, and is aberrantly expressed in some types of cancers. The present study focuses on identifying the o...

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Bibliographic Details
Main Authors: Fenfen Wang, Qin Chen, Genping Huang, Xuedong Guo, Na Li, Yang Li, Baohua Li
Format: Article
Language:English
Published: BMC 2018-11-01
Series:BMC Cancer
Subjects:
Endometrial adenocarcinoma
BKCa
MEK1/2
ERK1/2
17β-estradiol
Prognosis
Online Access:http://link.springer.com/article/10.1186/s12885-018-5027-9

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http://link.springer.com/article/10.1186/s12885-018-5027-9

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