Conversion of stationary to invasive tumor initiating cells (TICs): role of hypoxia in membrane type 1-matrix metalloproteinase (MT1-MMP) trafficking.

Emerging evidence has implicated the role of tumor initiating cells (TICs) in the process of cancer metastasis. The mechanism underlying the conversion of TICs from stationary to invasive remains to be characterized. In this report, we employed less invasive breast cancer TICs, SK-3rd, that displays...

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Bibliographic Details
Main Authors: Jian Li, Stanley Zucker, Ashleigh Pulkoski-Gross, Cem Kuscu, Mihriban Karaayvaz, Jingfang Ju, Herui Yao, Erwei Song, Jian Cao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3367975?pdf=render