Normal mitochondrial function in Saccharomyces cerevisiae has become dependent on inefficient splicing

Self-splicing introns are mobile elements that have invaded a number of highly conserved genes in prokaryotic and organellar genomes. Here, we show that deletion of these selfish elements from the Saccharomyces cerevisiae mitochondrial genome is stressful to the host. A strain without mitochondrial...

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Bibliographic Details
Main Authors: Marina Rudan, Peter Bou Dib, Marina Musa, Matea Kanunnikau, Sandra Sobočanec, David Rueda, Tobias Warnecke, Anita Kriško
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-03-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/35330