Expression analysis of the osteoarthritis genetic susceptibility mapping to the matrix Gla protein gene MGP

Expression analysis of the osteoarthritis genetic susceptibility mapping to the matrix Gla protein gene MGP

Abstract Background Osteoarthritis (OA) is a common disease of older individuals that impacts detrimentally on the quality and the length of life. It is characterised by the painful loss of articular cartilage and is polygenic and multifactorial. Genome-wide association scans have highlighted over 9...

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Bibliographic Details
Main Authors: Colin Shepherd, Abigail E. Reese, Louise N. Reynard, John Loughlin
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Arthritis Research & Therapy
Subjects:
Osteoarthritis
Genetic association signal
MGP
Allelic expression
RNA interference
Knockdown
Online Access:http://link.springer.com/article/10.1186/s13075-019-1934-7

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http://link.springer.com/article/10.1186/s13075-019-1934-7

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