Autoinflammatory Diseases: Consequences of Uncontrolled Inflammasome Activation

Inflammasomes are sensors within the innate immune system that are responsible for the regulation of caspase-1 activation and the initiation of inflammatory responses following cellular infection or damage. A significant number of chronic inflammatory and metabolic diseases have recently been identi...

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Bibliographic Details
Main Authors: Sinéad Kenealy, Emma M. Creagh
Format: Article
Language:English
Published: European Medical Journal 2018-07-01
Series:European Medical Journal Allergy & Immunology
Subjects:
Online Access:https://www.emjreviews.com/allergy-immunology/article/autoinflammatory-diseases-consequences-of-uncontrolled-inflammasome-activation/