Acyclovir-Loaded Solid Lipid Nanoparticles: Optimization, Characterization and Evaluation of Its Pharmacokinetic Profile

Acyclovir-Loaded Solid Lipid Nanoparticles: Optimization, Characterization and Evaluation of Its Pharmacokinetic Profile

Acyclovir is an antiviral drug used for the treatment of <i>herpes simplex</i> virus infection. Its oral bioavailability is low; therefore, frequent and high doses are prescribed for optimum therapeutic efficacy. Moreover, the current therapeutic regimen of acyclovir is associated with u...

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Bibliographic Details
Main Authors: Haniza Hassan, Ramatu Omenesa Bello, Siti Khadijah Adam, Ekram Alias, Meor Mohd Redzuan Meor Mohd Affandi, Ahmad Fuad Shamsuddin, Rusliza Basir
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Nanomaterials
Subjects:
acyclovir
bioavailability
oral delivery
solid lipid nanoparticles
Online Access:https://www.mdpi.com/2079-4991/10/9/1785

Internet

https://www.mdpi.com/2079-4991/10/9/1785

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