Polymorphisms in ABC transporter genes and concentrations of mercury in newborns--evidence from two Mediterranean birth cohorts.

The genetic background may influence methylmercury (MeHg) metabolism and neurotoxicity. ATP binding cassette (ABC) transporters actively transport various xenobiotics across biological membranes.To investigate the role of ABC polymorphisms as modifiers of prenatal exposure to MeHg.The study populati...

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Main Authors: Sabrina Llop, Karin Engström, Ferran Ballester, Elisa Franforte, Ayman Alhamdow, Federica Pisa, Janja Snoj Tratnik, Datja Mazej, Mario Murcia, Marisa Rebagliato, Mariona Bustamante, Jordi Sunyer, Alphaikaterini Sofianou-Katsoulis, Alexia Prasouli, Eleni Antonopoulou, Ioanna Antoniadou, Sheena Nakou, Fabio Barbone, Milena Horvat, Karin Broberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4022503?pdf=render