Amyloid-β peptide binds to cytochrome C oxidase subunit 1.

Extracellular and intraneuronal accumulation of amyloid-beta aggregates has been demonstrated to be involved in the pathogenesis of Alzheimer's disease (AD). However, the precise mechanism of amyloid-beta neurotoxicity is not completely understood. Previous studies suggest that binding of amylo...

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Bibliographic Details
Main Authors: Luis Fernando Hernandez-Zimbron, Jose Luna-Muñoz, Raul Mena, Ricardo Vazquez-Ramirez, Carlos Kubli-Garfias, David H Cribbs, Karen Manoutcharian, Goar Gevorkian
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22927926/?tool=EBI