LDL particle subclasses in hypercholesterolemia: molecular determinants of reduced lipid hydroperoxide stability

LDL particle subclasses in hypercholesterolemia: molecular determinants of reduced lipid hydroperoxide stability

Hypercholesterolemia is characterized by elevated plasma levels of LDL in which the cholesteryl ester (CE)-rich LDL subclasses of light and intermediate density (LDL1+2 and LDL3, respectively) typically predominate. The molecular mechanisms implicated in oxidation of LDL particle subclasses in hyper...

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Bibliographic Details
Main Authors: Laurent Chancharme, Patrice Thérond, Fabienne Nigon, Stéphanie Zarev, Alain Mallet, Eric Bruckert, M. John Chapman
Format: Article
Language:English
Published: Elsevier 2002-03-01
Series:Journal of Lipid Research
Subjects:
light, intermediate, and dense LDL
oxidative stress
copper-mediated oxidation
surface phospholipid-free cholesterol ratio
polyunsaturated cholesteryl ester-α-tocopherol ratio
lipophilic antioxidants
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520301528

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http://www.sciencedirect.com/science/article/pii/S0022227520301528

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