A Novel PhoP/PhoQ Regulation Pathway Modulates the Survival of Extraintestinal Pathogenic Escherichia coli in Macrophages

A Novel PhoP/PhoQ Regulation Pathway Modulates the Survival of Extraintestinal Pathogenic Escherichia coli in Macrophages

The extraintestinal pathogenic Escherichia coli (ExPEC) is a typical facultative intracellular bacterial pathogen. Sensing the environmental stimuli and undertaking adaptive change are crucial for ExPEC to successfully colonize in specific extraintestinal niches. The previous studies show that patho...

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Bibliographic Details
Main Authors: Xiangkai Zhuge, Yu Sun, Feng Xue, Fang Tang, Jianluan Ren, Dezhi Li, Juanfang Wang, Min Jiang, Jianjun Dai
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Immunology
Subjects:
extraintestinal pathogenic Escherichia coli
macrophages
PhoP/PhoQ
ColV plasmid
HlyF
autophagosome
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00788/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00788/full

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