Reprogramming of Urine-Derived Renal Epithelial Cells into iPSCs Using srRNA and Consecutive Differentiation into Beating Cardiomyocytes

Reprogramming of Urine-Derived Renal Epithelial Cells into iPSCs Using srRNA and Consecutive Differentiation into Beating Cardiomyocytes

The generation of induced pluripotent stem cells (iPSCs) from patient’s somatic cells and the subsequent differentiation into desired cell types opens up numerous possibilities in regenerative medicine and tissue engineering. Adult cardiomyocytes have limited self-renewal capacity; thus, the efficie...

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Bibliographic Details
Main Authors: Heidrun Steinle, Marbod Weber, Andreas Behring, Ulrike Mau-Holzmann, Christiane von Ohle, Aron-Frederik Popov, Christian Schlensak, Hans Peter Wendel, Meltem Avci-Adali
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Molecular Therapy: Nucleic Acids
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253119302069

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http://www.sciencedirect.com/science/article/pii/S2162253119302069

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