Chitosan Aerogel Catalyzed Asymmetric Aldol Reaction in Water: Highly Enantioselective Construction of 3-Substituted-3-hydroxy-2-oxindoles

Chitosan Aerogel Catalyzed Asymmetric Aldol Reaction in Water: Highly Enantioselective Construction of 3-Substituted-3-hydroxy-2-oxindoles

A chitosan aerogel catalyzed asymmetric aldol reaction of ketones with isatins in the presence of water is described. This protocol was found to be environmentally benign, because it proceeds smoothly in water and the corresponding aldol products were obtained in excellent yields with good enantiose...

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Bibliographic Details
Main Authors: Hui Dong, Jie Liu, Lifang Ma, Liang Ouyang
Format: Article
Language:English
Published: MDPI AG 2016-11-01
Series:Catalysts
Subjects:
chitosan aerogel
aldol reaction
water
isatin
Online Access:http://www.mdpi.com/2073-4344/6/12/186

Internet

http://www.mdpi.com/2073-4344/6/12/186

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