Enhanced IL-6/IL-6R signaling promotes growth and malignant properties in EBV-infected premalignant and cancerous nasopharyngeal epithelial cells.

Enhanced IL-6/IL-6R signaling promotes growth and malignant properties in EBV-infected premalignant and cancerous nasopharyngeal epithelial cells.

Nasopharyngeal carcinoma (NPC) is etiologically associated with Epstein-Barr virus (EBV) infection. However, the exact role of EBV in NPC pathogenesis remains elusive. Activation of signal transducer and activator of transcription 3 (STAT3) is common in human cancers including NPC and plays an impor...

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Bibliographic Details
Main Authors: Guitao Zhang, Chi Man Tsang, Wen Deng, Yim Ling Yip, Vivian Wai-Yan Lui, Sze Chuen Cesar Wong, Annie Lai-Man Cheung, Pok Man Hau, Musheng Zeng, Maria Li Lung, Honglin Chen, Kwok Wai Lo, Kenzo Takada, Sai Wah Tsao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23658720/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23658720/?tool=EBI

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