Synthesis and Evaluation of N-(3-Trifluoroacetylindol- 7-yl) Acetamides for Potential In Vitro Antiplasmodial Properties

A series of novel N-((2,5-diaryl-3-trifluoroacetyl)-1H-indol-7-yl)acetamides has been prepared via a successive and one-pot reaction sequence involving initial trifluoroacetic acid-mediated Beckmann rearrangement of the oximes derived from the 1-(2,5-diaryl-1H-indol-7-yl)ethanones, followed by trifl...

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Bibliographic Details
Main Authors: Malose J., Mphahlele (Author), Mmakwena M., Mmonwa (Author), Yee, Siew Choong (Author)
Format: Article
Language:English
Published: MDPI, 2017.
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