Quantification of Dynamic 11C-Phenytoin PET Studies

Quantification of Dynamic 11C-Phenytoin PET Studies

The overexpression of P-glycoprotein (Pgp) is thought to be an important mechanism of pharmacoresistance in epilepsy. Recently, 11C-phenytoin has been evaluated preclinically as a tracer for Pgp. The aim of the present study was to assess the optimal plasma kinetic model for quantification of 11C-ph...

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Bibliographic Details
Main Authors: Mansor, Mohd Syahir (Author), Boellaard, Ronald (Author), Froklage, Femke E. (Author), Bakker, Esther D.M (Author), Yaqub, Maqsood (Author), Voskuyl, Rob A. (Author), Schwarte, Lothar A. (Author), Verbeek, Joost (Author), Windhorst, Albert D. (Author), Lammertsma, Adriaan (Author)
Format: Article
Language:English
Published: Society of Nuclear Medicine, 2015-09.
Subjects:
RM300-666 Drugs and their actions
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