Quantification of Dynamic 11C-Phenytoin PET Studies
The overexpression of P-glycoprotein (Pgp) is thought to be an important mechanism of pharmacoresistance in epilepsy. Recently, 11C-phenytoin has been evaluated preclinically as a tracer for Pgp. The aim of the present study was to assess the optimal plasma kinetic model for quantification of 11C-ph...
Main Authors: | Mansor, Mohd Syahir (Author), Boellaard, Ronald (Author), Froklage, Femke E. (Author), Bakker, Esther D.M (Author), Yaqub, Maqsood (Author), Voskuyl, Rob A. (Author), Schwarte, Lothar A. (Author), Verbeek, Joost (Author), Windhorst, Albert D. (Author), Lammertsma, Adriaan (Author) |
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Format: | Article |
Language: | English |
Published: |
Society of Nuclear Medicine,
2015-09.
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Subjects: | |
Online Access: | Get fulltext |
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