Rational approach to the selection of conditions for diastereomeric resolution of chiral amines by diacid resolving agents

This paper presents an experimental and modelling approach to understanding the key conditions for diastereomeric resolutions of chiral amines by diacid resolving agents. The model is used to calculate resolution yields and enantiomeric excesses on the basis of acidâ€"base chemical equilibria,...

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Bibliographic Details
Main Authors: Ferreira, Frederico (Author), Ghazali, Nazlee Faisal (Author), Cocchini, Ugo (Author), Livingston, Andrew (Author)
Format: Article
Language:English
Published: Elsevier, 2006.
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