β-sheet containment by flanking prolines: Molecular Dynamic Simulations of the inhibition of β-sheet elongation by proline residues in human prion protein.
Previous molecular dynamic simulations have reported elongation of the existing β-sheet in prion proteins. Detailed examination has shown that these elongations do not extend beyond the proline residues flanking these β-sheets. In addition, proline has also been suggested to possess a possible s...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Biophysical Society,
2007-03-15.
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| Subjects: | |
| Online Access: | Get fulltext |