Structural analysis of platelet-derived growth factor receptor alpha by protein homology modeling
Constitutive phosphorylation activity by receptor tyrosine kinases due to activating mutations have been linked to human malignancies. Substitution mutation of tyrosine 849 to serine residue led to the constitutive phosphorylation of platelet-derived growth factor receptor alpha (PDGFRa) as found in...
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| Format: | Thesis |
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2015-02.
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| Online Access: | Get fulltext |