Development of fed-batch cultivation strategy for efficient oxytetracycline production by streptomyces rimosus at semi-industrial scale
Oxytetracycline (OTC) production by Streptomyces rimosus was studied in batch and fed-batch cultures in shake flask and bioreactor levels using semi-defined medium. First, the effect of glucose concentration on OTC production and growth kinetics was studied intensively. The optimal glucose concentra...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Instituto de Tecnologia do Parana,
2015.
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Subjects: | |
Online Access: | Get fulltext |