The Chromatin Regulator CHD8 Is a Context-Dependent Mediator of Cell Survival in Murine Hematopoietic Malignancies
Aberrant chromatin regulation is a frequent driver of leukemogenesis. Mutations in chromatin regulators often result in more stem-like cells that seed a bulk leukemic population. Inhibitors targeting these proteins represent an emerging class of therapeutics, and identifying further chromatin regula...
| Main Authors: | , |
|---|---|
| Other Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science,
2016-01-04T14:50:30Z.
|
| Subjects: | |
| Online Access: | Get fulltext |