Calibrating the Human Mutation Rate via Ancestral Recombination Density in Diploid Genomes

Calibrating the Human Mutation Rate via Ancestral Recombination Density in Diploid Genomes

The human mutation rate is an essential parameter for studying the evolution of our species, interpreting present-day genetic variation, and understanding the incidence of genetic disease. Nevertheless, our current estimates of the rate are uncertain. Most notably, recent approaches based on countin...

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Main Authors: Lipson, Mark (Author), Loh, Po-Ru (Author), Sankararaman, Sriram (Author), Patterson, Nick (Author), Berger, Bonnie (Contributor), Reich, David (Author)
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory (Contributor), Massachusetts Institute of Technology. Department of Mathematics (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2016-01-04T18:37:11Z.
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