Evidence of Abundant Purifying Selection in Humans for Recently Acquired Regulatory Functions
Although only 5% of the human genome is conserved across mammals, a substantially larger portion is biochemically active, raising the question of whether the additional elements evolve neutrally or confer a lineage-specific fitness advantage. To address this question, we integrate human variation in...
Main Authors: | , |
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Other Authors: | , |
Format: | Article |
Language: | English |
Published: |
American Association for the Advancement of Science (AAAS),
2016-01-06T17:21:37Z.
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Subjects: | |
Online Access: | Get fulltext |