Allosteric activation of apicomplexan calcium-dependent protein kinases

Allosteric activation of apicomplexan calcium-dependent protein kinases

Calcium-dependent protein kinases (CDPKs) comprise the major group of Ca[superscript 2+]-regulated kinases in plants and protists. It has long been assumed that CDPKs are activated, like other Ca[superscript 2+]-regulated kinases, by derepression of the kinase domain (KD). However, we found that rem...

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Main Authors: Ingram, Jessica R. (Author), Markus, Benedikt M. (Author), Mandelbaum, Joseph (Author), Ramek, Alexander (Author), Shan, Yibing (Author), Shaw, David E. (Author), Lourido, Sebastian (Author), Schwartz, Thomas (Contributor), Ploegh, Hidde (Contributor), Knockenhauer, Kevin Edward (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor), Knockenhauer, Kevin E. (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2016-02-05T14:20:38Z.
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