Metabolic fate of endogenous molecular damage: Urinary glutathione conjugates of DNA-derived base propenals as markers of inflammation

Although mechanistically linked to disease, cellular molecules damaged by endogenous processes have not emerged as significant biomarkers of inflammation and disease risk, due in part to poor understanding of their pharmacokinetic fate from tissue to excretion. Here, we use systematic metabolite pro...

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Bibliographic Details
Main Authors: Jumpathong, Watthanachai (Contributor), Chan, Wan (Author), Taghizadeh, Koli (Contributor), Dedon, Peter C. (Contributor), Indrakanti, Ramesh Babu (Contributor)
Other Authors: Massachusetts Institute of Technology. Center for Environmental Health Sciences (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2016-02-05T14:56:49Z.
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