In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight

In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight

Dysfunctional endothelium contributes to more diseases than any other tissue in the body. Small interfering RNAs (siRNAs) can help in the study and treatment of endothelial cells in vivo by durably silencing multiple genes simultaneously, but efficient siRNA delivery has so far remained challenging....

Full description

Bibliographic Details
Main Authors: Dahlman, James E. (Contributor), Jhunjhunwala, Siddharth (Contributor), Shaw, Taylor E. (Contributor), Xing, Yiping (Contributor), Sahay, Gaurav (Contributor), Bader, Andrew (Contributor), Yin, Hao (Contributor), Dong, Yizhou (Contributor), Jiang, Shan (Contributor), Seedorf, Danielle (Contributor), Dave, Apeksha (Contributor), Sandhu, Kamaljeet Singh (Contributor), Webber, Matthew (Contributor), Lytton-Jean, Abigail K. R. (Contributor), Levins, Christopher G. (Contributor), Anderson, Daniel Griffith (Contributor), Khan, Omar Fizal (Author), Bogorad, Roman (Author), Ruda, Vera (Author), Langer, Robert S (Author)
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Khan, Omar F. (Contributor), Bogorad, Roman L. (Contributor), Ruda, Vera M. (Contributor), Langer, Robert (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2016-02-09T15:35:33Z.
Subjects:
Article
Online Access:Get fulltext

Internet

Get fulltext

Similar Items