Organ-targeted high-throughput in vivo biologics screen identifies materials for RNA delivery

Organ-targeted high-throughput in vivo biologics screen identifies materials for RNA delivery

Therapies based on biologics involving delivery of proteins, DNA, and RNA are currently among the most promising approaches. However, although large combinatorial libraries of biologics and delivery vehicles can be readily synthesized, there are currently no means to rapidly characterize them in viv...

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Main Authors: Chang, Tsung-Yao (Contributor), Chatnuntawech, Itthi (Contributor), Yanik, Mehmet Fatih (Contributor), Tillberg, Paul W. (Contributor), Eimon, Peter (Contributor), Anderson, Daniel Griffith (Contributor), Shi, Peng, Ph. D. Massachusetts Institute of Technology (Author), Steinmeyer, Joseph Daly (Author), Love, Kevin T (Author)
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor), Massachusetts Institute of Technology. Research Laboratory of Electronics (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Shi, Peng (Contributor), Steinmeyer, Joseph D. (Contributor), Love, Kevin T. (Contributor)
Format: Article
Language:English
Published: Royal Society of Chemistry, 2016-02-09T18:02:55Z.
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