A mucosal vaccine against Chlamydia trachomatis generates two waves of protective memory T cells
Genital Chlamydia trachomatis (Ct) infection induces protective immunity that depends on interferon-γ-producing CD4 T cells. By contrast, we report that mucosal exposure to ultraviolet light (UV)-inactivated Ct (UV-Ct) generated regulatory T cells that exacerbated subsequent Ct infection. We show th...
Main Authors: | , , , , , , , , , , , , , , |
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Other Authors: | , |
Format: | Article |
Language: | English |
Published: |
American Association for the Advancement of Science (AAAS),
2016-02-17T21:52:11Z.
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Subjects: | |
Online Access: | Get fulltext |