Nanowell-Based Immunoassays for Measuring Single-Cell Secretion: Characterization of Transport and Surface Binding

Arrays of subnanoliter wells (nanowells) provide a useful system to isolate single cells and analyze their secreted proteins. Two general approaches have emerged: one that uses open arrays and local capture of secreted proteins, and a second (called microengraving) that relies on closed arrays to ca...

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Bibliographic Details
Main Authors: Torres, Alexis J. (Contributor), Hill, Abby (Contributor), Love, John C (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Love, J. Christopher (Contributor)
Format: Article
Language:English
Published: American Chemical Society (ACS), 2016-02-19T02:20:54Z.
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