Neutralizing antibodies against West Nile virus identified directly from human B cells by single-cell analysis and next generation sequencing

Neutralizing antibodies against West Nile virus identified directly from human B cells by single-cell analysis and next generation sequencing

West Nile virus (WNV) infection is an emerging mosquito-borne disease that can lead to severe neurological illness and currently has no available treatment or vaccine. Using microengraving, an integrated single-cell analysis method, we analyzed a cohort of subjects infected with WNV - recently infec...

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Main Authors: Tsioris, Konstantinos (Contributor), Gupta, Namita T. (Author), Ogunniyi, Adebola Oluwakayode (Contributor), Qian, Feng (Author), Yao, Yi (Author), Wang, Xiaomei (Author), Stern, Joel N. H. (Author), Chari, Raj (Author), Briggs, Adrian W. (Author), Clouser, Christopher R. (Author), Vigneault, Francois (Author), Church, George M. (Author), Garcia, Melissa N. (Author), Murray, Kristy O. (Author), Montgomery, Ruth R. (Author), Kleinstein, Steven H. (Author), Love, J. Christopher (Contributor), Zimnisky, Ross Martin (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Royal Society of Chemistry, 2016-02-19T02:59:08Z.
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