On the dual effect of glucose during production of pBAD/AraC-based minicircles

Minicircles are promising vectors for DNA vaccination, gene or cell therapies due to their increased transfection efficacy and transgene expression. The in vivo production of these novel vectors involves the arabinose inducible excision of a parental molecule into a minicircircle and a miniplasmid b...

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Bibliographic Details
Main Authors: Simcikova, Michaela (Contributor), Monteiro, Gabriel A. (Author), Prather, Kristala L. Jones (Contributor), Prazeres, Duarte M. F. (Contributor)
Other Authors: MIT-Portugal Program (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor)
Format: Article
Language:English
Published: Elsevier, 2016-02-23T19:20:54Z.
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