On the dual effect of glucose during production of pBAD/AraC-based minicircles
Minicircles are promising vectors for DNA vaccination, gene or cell therapies due to their increased transfection efficacy and transgene expression. The in vivo production of these novel vectors involves the arabinose inducible excision of a parental molecule into a minicircircle and a miniplasmid b...
Main Authors: | , , , |
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Other Authors: | , |
Format: | Article |
Language: | English |
Published: |
Elsevier,
2016-02-23T19:20:54Z.
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Subjects: | |
Online Access: | Get fulltext |