Imaging Primary Lung Cancers in Mice to Study Radiation Biology

Imaging Primary Lung Cancers in Mice to Study Radiation Biology

Purpose To image a genetically engineered mouse model of non-small-cell lung cancer with micro-computed tomography (micro-CT) to measure tumor response to radiation therapy. Methods and Materials The Cre-loxP system was used to generate primary lung cancers in mice with mutation in K-ras alone or in...

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Main Authors: Kirsch, David G. (Contributor), Grimm, Jan (Author), Guimaraes, Alexander R. (Author), Wojtkiewicz, Gregory R. (Author), Perez, Bradford A. (Author), Santiago, Philip M. (Contributor), Anthony, Nikolas K. (Author), Forbes, Thomas (Author), Doppke, Karen (Author), Weissleder, Ralph (Author), Jacks, Tyler E (Author)
Other Authors: Koch Institute for Integrative Cancer Research at MIT (Contributor), Jacks, Tyler E. (Contributor)
Format: Article
Language:English
Published: Elsevier, 2016-02-24T17:11:59Z.
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