Nkx2-1 Represses a Latent Gastric Differentiation Program in Lung Adenocarcinoma

Nkx2-1 Represses a Latent Gastric Differentiation Program in Lung Adenocarcinoma

Tissue-specific differentiation programs become dysregulated during cancer evolution. The transcription factor Nkx2-1 is a master regulator of pulmonary differentiation that is downregulated in poorly differentiated lung adenocarcinoma. Here we use conditional murine genetics to determine how the id...

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Main Authors: Snyder, Eric L (Author), Watanabe, Hideo (Author), Magendantz, Margaret (Contributor), Hoersch, Sebastian (Contributor), Chen, Tiffany A (Author), Wang, Diana G (Author), Whittaker, Charles A (Author), Meyerson, Matthew L. (Author), Kimura, Shioko (Author), Chen, Tiffany A. (Contributor), Wang, Diana G. (Contributor), Whittaker, Charles A. (Contributor), Crowley, Denise G. (Author), Jacks, Tyler E (Author), Snyder, Eric (Author)
Other Authors: Koch Institute for Integrative Cancer Research at MIT (Contributor), Snyder, Eric L. (Contributor), Crowley, Denise (Contributor), Jacks, Tyler E. (Contributor)
Format: Article
Language:English
Published: Elsevier, 2016-02-24T17:37:40Z.
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