Differential regulation of evoked and spontaneous neurotransmitter release by C-terminal modifications of complexin

Differential regulation of evoked and spontaneous neurotransmitter release by C-terminal modifications of complexin

Complexins are small α-helical proteins that modulate neurotransmitter release by binding to SNARE complexes during synaptic vesicle exocytosis. They have been found to function as fusion clamps to inhibit spontaneous synaptic vesicle fusion in the absence of Ca[superscript 2+], while also promoting...

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Main Authors: Akbergenova, Yulia (Contributor), Huntwork-Rodriguez, Sarah (Contributor), Volfson, Dina (Contributor), Littleton, J. Troy (Contributor), Buhl, Lauren Kaye (Author), Jorquera, Ramon (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), Picower Institute for Learning and Memory (Contributor), Buhl, Lauren K. (Contributor), Jorquera, Ramon A. (Contributor)
Format: Article
Language:English
Published: Elsevier, 2016-02-25T14:56:13Z.
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