Chromatin Dynamics and the RNA Exosome Function in Concert to Regulate Transcriptional Homeostasis

Chromatin Dynamics and the RNA Exosome Function in Concert to Regulate Transcriptional Homeostasis

The histone variant H2A.Z is a hallmark of nucleosomes flanking promoters of protein-coding genes and is often found in nucleosomes that carry lysine 56-acetylated histone H3 (H3-K56Ac), a mark that promotes replication-independent nucleosome turnover. Here, we find that H3-K56Ac promotes RNA polyme...

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Main Authors: Rege, Mayuri (Author), Subramanian, Vidya (Contributor), Zhu, Chenchen (Author), Hsieh, Tsung-Han S (Author), Weiner, Assaf (Author), Friedman, Nir (Author), Steinmetz, Lars M (Author), Rando, Oliver J (Author), Peterson, Craig L (Author), Clauder-Munster, Sandra (Author), Boyer, Laurie Ann (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Boyer, Laurie (Contributor)
Format: Article
Language:English
Published: Elsevier, 2016-03-15T00:14:43Z.
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