Localized epigenetic silencing of a damage-activated WNT enhancer limits regeneration in mature Drosophila imaginal discs

Many organisms lose the capacity to regenerate damaged tissues as they mature. Damaged Drosophila imaginal discs regenerate efficiently early in the third larval instar (L3) but progressively lose this ability. This correlates with reduced damage-responsive expression of multiple genes, including th...

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Bibliographic Details
Main Authors: Setiawan, Linda (Author), Saul, Joshua Clayton (Contributor), Harris, Robin E. (Author), Hariharan, Iswar K. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: eLife Sciences Publications, Ltd., 2016-03-16T16:10:13Z.
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