Bistability of a coupled Aurora B kinase-phosphatase system in cell division

Bistability of a coupled Aurora B kinase-phosphatase system in cell division

Aurora B kinase, a key regulator of cell division, localizes to specific cellular locations, but the regulatory mechanisms responsible for phosphorylation of substrates located remotely from kinase enrichment sites are unclear. Here, we provide evidence that this activity at a distance depends on bo...

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Bibliographic Details
Main Authors: Godzi, Maxim (Author), Calderon, Abram (Author), Stamatov, Rumen (Author), Zaytsev, Anatoly V. (Author), Segura-Pena, Dario (Author), Ballister, Edward R. (Author), Mayo, Alyssa M. (Author), Black, Ben E. (Author), Ataullakhanov, Fazly I. (Author), Lampson, Michael A. (Author), Grishchuk, Ekaterina L. (Author), Peterson, Laura B (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor), Peterson, Laura (Contributor)
Format: Article
Language:English
Published: eLife Sciences Publications, Ltd., 2016-03-16T17:35:08Z.
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