Neural innervation stimulates splenic TFF2 to arrest myeloid cell expansion and cancer

Neural innervation stimulates splenic TFF2 to arrest myeloid cell expansion and cancer

CD11b[superscript +]Gr-1[superscript +] myeloid-derived suppressor cells (MDSCs) expand in the spleen during cancer and promote progression through suppression of cytotoxic T cells. An anti-inflammatory reflex arc involving the vagus nerve and memory T cells is necessary for resolution of acute infl...

Full description

Bibliographic Details
Main Authors: Dubeykovskaya, Zina (Author), Si, Yiling (Author), Chen, Xiaowei (Author), Worthley, Daniel L. (Author), Renz, Bernhard W. (Author), Urbanska, Aleksandra M. (Author), Hayakawa, Yoku (Author), Xu, Ting (Author), Westphalen, C. Benedikt (Author), Dubeykovskiy, Alexander (Author), Chen, Duan (Author), Friedman, Richard A. (Author), Asfaha, Samuel (Author), Nagar, Karan (Author), Tailor, Yagnesh (Author), Muthupalani, Sureshkumar (Contributor), Fox, James G. (Contributor), Kitajewski, Jan (Author), Wang, Timothy C. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Division of Comparative Medicine (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2016-03-16T20:13:58Z.
Subjects:
Article
Online Access:Get fulltext

Internet

Get fulltext

Similar Items