HDL-Mimetic PLGA Nanoparticle To Target Atherosclerosis Plaque Macrophages

HDL-Mimetic PLGA Nanoparticle To Target Atherosclerosis Plaque Macrophages

High-density lipoprotein (HDL) is a natural nanoparticle that exhibits an intrinsic affinity for atherosclerotic plaque macrophages. Its natural targeting capability as well as the option to incorporate lipophilic payloads, e.g., imaging or therapeutic components, in both the hydrophobic core and th...

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Main Authors: Sanchez-Gaytan, Brenda L. (Author), Fay, Francois (Author), Lobatto, Mark E. (Author), Tang, Jun (Author), Ouimet, Mireille (Author), Kim, YongTae (Author), van der Staay, Susanne E. M. (Author), van Rijs, Sarian M. (Author), Priem, Bram (Author), Zhang, Liangfang (Author), Fisher, Edward A. (Author), Moore, Kathryn J. (Author), Fayad, Zahi A. (Author), Mulder, Willem J. M. (Author), Langer, Robert S (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Langer, Robert (Contributor)
Format: Article
Language:English
Published: American Chemical Society (ACS), 2016-03-24T15:18:34Z.
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