High-bandwidth AFM-based rheology is a sensitive indicator of early cartilage aggrecan degradation relevant to mouse models of osteoarthritis

High-bandwidth AFM-based rheology is a sensitive indicator of early cartilage aggrecan degradation relevant to mouse models of osteoarthritis

Murine models of osteoarthritis (OA) and post-traumatic OA have been widely used to study the development and progression of these diseases using genetically engineered mouse strains along with surgical or biochemical interventions. However, due to the small size and thickness of murine cartilage, t...

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Bibliographic Details
Main Authors: Gauci, Stephanie J. (Author), Frank, Eliot (Contributor), Fosang, Amanda J. (Author), Ortiz, Christine (Contributor), Grodzinsky, Alan J. (Contributor), Tavakoli Nia, Hadi (Contributor), Azadi Sohi, Mojtaba (Contributor), Hung, Han-Hwa K. (Contributor)
Other Authors: Massachusetts Institute of Technology. Center for Biomedical Engineering (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor), Massachusetts Institute of Technology. Department of Materials Science and Engineering (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor)
Format: Article
Language:English
Published: Elsevier, 2016-04-01T15:05:47Z.
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