Optogenetic drive of neocortical pyramidal neurons generates fMRI signals that are correlated with spiking activity

Optogenetic drive of neocortical pyramidal neurons generates fMRI signals that are correlated with spiking activity

Local fluctuations in the blood oxygenation level-dependent (BOLD) signal serve as the basis of functional magnetic resonance imaging (fMRI). Understanding the correlation between distinct aspects of neural activity and the BOLD response is fundamental to the interpretation of this widely used mappi...

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Bibliographic Details
Main Authors: Kahn, I. (Author), Knoblich, Ulf (Contributor), Desai, Mitul (Contributor), Bernstein, Jacob G. (Contributor), Moore, Christopher I. (Contributor), Buckner, R. L. (Author), Graybiel, Ann M (Author), Boyden, Edward (Author)
Other Authors: Massachusetts Institute of Technology. Synthetic Neurobiology Group (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Media Laboratory (Contributor), McGovern Institute for Brain Research at MIT (Contributor), Program in Media Arts and Sciences (Massachusetts Institute of Technology) (Contributor), Graybiel, Ann M. (Contributor), Boyden, Edward Stuart (Contributor)
Format: Article
Language:English
Published: Elsevier, 2016-04-08T16:27:44Z.
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