Aneuploidy-induced cellular stresses limit autophagic degradation

Aneuploidy-induced cellular stresses limit autophagic degradation

An unbalanced karyotype, a condition known as aneuploidy, has a profound impact on cellular physiology and is a hallmark of cancer. Aneuploid cells experience a number of stresses that are caused by aneuploidy-induced proteomic changes. How the aneuploidy-associated stresses affect cells and whether...

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Bibliographic Details
Main Authors: Santaguida, Stefano (Contributor), Vasile, Eliza (Contributor), White, Eileen (Author), Amon, Angelika B (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Amon, Angelika B. (Contributor)
Format: Article
Language:English
Published: Cold Spring Harbor Laboratory Press, 2016-04-19T15:18:29Z.
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