A phylogenetic analysis using full-length viral genomes of South American dengue serotype 3 in consecutive Venezuelan outbreaks reveals a novel NS5 mutation

A phylogenetic analysis using full-length viral genomes of South American dengue serotype 3 in consecutive Venezuelan outbreaks reveals a novel NS5 mutation

Dengue virus currently causes 50-100 million infections annually. Comprehensive knowledge about the evolution of Dengue in response to selection pressure is currently unavailable, but would greatly enhance vaccine design efforts. In the current study, we sequenced 187 new dengue virus serotype 3 (DE...

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Main Authors: Camacho, D. (Author), Comach, G. (Author), Xhaja, K. (Author), Rizzolo, K. (Author), de Bosch, N. (Author), Becerra, A. (Author), Mondini, A. (Author), Ocazionez, R. (Author), Bosch, Irene (Author), Gehrke, Lee (Contributor), Schmidt, D. J. (Author), Pickett, B. E. (Author), Lennon, N. J. (Author), Nogueira, Mauricio Lacerda (Author), da Silva, E. V. (Author), Vasconcelos, P. F. (Author), Munoz-Jordan, J. L. (Author), Santiago, G. A. (Author), Lefkowitz, E. J. (Author), Birren, B. W. (Author), Henn, M. R. (Author)
Other Authors: Institute for Medical Engineering and Science (Contributor)
Format: Article
Language:English
Published: Elsevier, 2016-04-20T17:04:19Z.
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