Stent elution rate determines drug deposition and receptor-mediated effects

Drug eluting stent designs abound and yet the dependence of efficacy on drug dose and elution duration remains unclear. We examined these issues within a mathematical framework of arterial drug distribution and receptor binding following stent elution. Model predictions that tissue content linearly...

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Bibliographic Details
Main Authors: Tzafriri, Abraham R. (Contributor), Groothuis, Adam (Author), Price, G. Sylvester (Author), Edelman, Elazer R. (Contributor)
Other Authors: Harvard University- (Contributor)
Format: Article
Language:English
Published: Elsevier, 2016-04-28T12:35:17Z.
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