Normal Midbrain Dopaminergic Neuron Development and Function in miR-133b Mutant Mice

Midbrain dopaminergic (mDA) neurons control movement and emotion, and their degeneration leads to motor and cognitive defects in Parkinson's disease (PD). miR-133b is a conserved microRNA that is thought to regulate mDA neuron differentiation by targeting Pitx3, a transcription factor required...

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Bibliographic Details
Main Authors: Heyer, Mary P. (Author), Pani, Amar K. (Author), Smeyne, Richard J. (Author), Kenny, Paul K. (Author), Feng, Guoping (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), McGovern Institute for Brain Research at MIT (Contributor)
Format: Article
Language:English
Published: Society for Neuroscience, 2016-05-05T00:08:20Z.
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