Cell type-specific plasticity of striatal projection neurons in parkinsonism and L-DOPA-induced dyskinesia

Cell type-specific plasticity of striatal projection neurons in parkinsonism and L-DOPA-induced dyskinesia

The striatum is widely viewed as the fulcrum of pathophysiology in Parkinson's disease (PD) and L-DOPA-induced dyskinesia (LID). In these disease states, the balance in activity of striatal direct pathway spiny projection neurons (dSPNs) and indirect pathway spiny projection neurons (iSPNs) is...

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Main Authors: Fieblinger, Tim (Author), Graves, Steven M. (Author), Sebel, Luke E. (Author), Alcacer, Cristina (Author), Plotkin, Joshua L. (Author), Gertler, Tracy S. (Author), Chan, C. Savio (Author), Heiman, Myriam (Contributor), Greengard, Paul (Author), Cenci, M. Angela (Author), Surmeier, D. James (Author)
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), Picower Institute for Learning and Memory (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2016-05-09T16:24:40Z.
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