Optical control of mammalian endogenous transcription and epigenetic states

Optical control of mammalian endogenous transcription and epigenetic states

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The dynamic nature of gene expression enables cellular programming, homeostasis and environmental adaptation in living systems. Dissection of causal gene functions in cellular and organismal processes therefore necessitates approaches that enable spatially and temporally precise modulation of gene e...

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Bibliographic Details
Main Authors: Konermann, Silvana M. (Contributor), Brigham, Mark D. (Contributor), Trevino, Alexandro E. (Contributor), Hsu, Patrick (Contributor), Heidenreich, Matthias (Contributor), Cong, Le (Contributor), Platt, Randall Jeffrey (Contributor), Scott, David Arthur (Contributor), Church, George M. (Author), Zhang, Feng (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), McGovern Institute for Brain Research at MIT (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2016-05-26T20:36:43Z.
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