A single-molecule characterization of p53 search on DNA
The tumor suppressor p53 slides along DNA while searching for its cognate site. Central to this process is the basic C-terminal domain, whose regulatory role and its coordination with the core DNA-binding domain is highly debated. Here we use single-molecule techniques to characterize the search pro...
| Main Authors: | , , , , |
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| Other Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
National Academy of Sciences (U.S.),
2016-06-02T20:55:13Z.
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| Subjects: | |
| Online Access: | Get fulltext |